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Weight of evidence: Overall evidence is Low-Moderate: multiple animal studies and a growing number of small clinical trials suggest benefits across gutbrain signaling, social and behavioral domains, gastrointestinal symptoms, and neurophysiological patterns, yet most human studies rely on caregiver-reported outcomes, lack biomarker integration, and seldom control for diet, comorbidities, or baseline microbiome composition

Thus, the free radical scavenging ability of DPPH reflects its ability to accept hydrogen from the molecule of ascorbic acid and the surface functional groups of FN-CDs and Z-FN-CDs to form a stable DPPH-H complex (Fig

Emendack et al., 2018

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